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A Neanderthal OAS1 Isoform

October 28, 2021October 24, 2021 by 5prime

A Neanderthal OAS1 Isoform Protects European Ancestry Individuals Against COVID-19 Susceptibility and Severity. Zhou et al, Nature Medicine, 2021

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Vitamin D and COVID-19

October 28, 2021October 24, 2021 by 5prime

Vitamin D and COVID-19 susceptibility and severity in the COVID-19 Host Genetics Initiative: A Mendelian randomization study. Butler-Laporte et al, PLOS Medicine, 2021

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Development of a Polygenic

October 28, 2021October 24, 2021 by 5prime

Development of a Polygenic Risk Score to Improve Screening for Fracture Risk: A Genetic Risk Prediction Study. Forgetta et al, PLOS Medicine, 2020

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Genome-wide association study

October 28, 2021October 24, 2021 by 5prime

Genome-wide association study for vitamin D levels reveals 69 independent loci. Manousaki et al, Am J of Human Genetics, 2020

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Genetic predisposition to increased

October 28, 2021October 24, 2021 by 5prime

Genetic predisposition to increased serum calcium, bone mineral density, and fracture risk in individuals with normal calcium levels: mendelian randomisation study. Cerani et al, BMJ, 2019

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An Atlas of Human and Murine Genetic

October 28, 2021October 24, 2021 by 5prime

An Atlas of Human and Murine Genetic Influences on Osteoporosis. Morris et al, Nature Genetics, 2019

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Genetic architecture

October 28, 2021October 24, 2021 by 5prime

Genetic architecture: The shape of genetic contribution to human traits and disease. Timpson et al, Nature Reviews Genetics, 2018

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Whole-genome sequenc

October 28, 2021October 24, 2021 by 5prime

Whole-genome sequencing identifies of EN1 as a determinant of bone density and fracture, Zheng et al, Nature 2015

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Genetics of Osteoporosis

October 28, 2021October 24, 2021 by 5prime

Genetics of Osteoporosis from Genome-Wide Association Studies: Advances and Challenges. Richards et al, Nature Reviews Genetics, 2012

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Use of genome-wide association

October 28, 2021October 24, 2021 by 5prime

Use of genome-wide association studies for drug repositioning. Sanseau et al, Nature Biotechnology, 2012

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